Communities for Open Research Synthesis - integrating preclinical systematic reviews into the research pipeline
Alexandra Bannach-Brown
(Berlin Institute of Health)
Friederike Elisabeth Kohrs
(BIH QUEST Center for Responsible Research)
Sarah McCann
(Berlin Institute of Health at Charité)
Mala Karmakar
(Charite)
Sofija Vojvodic
Torsten Rackoll
Paper Short Abstract
The COReS project develops a framework to integrate systematic review into preclinical research through education, infrastructure, and community building. Piloted across Germany, COReS enhances research synthesis and incorporates evidence-based decision-making into preclinical research.
Paper Abstract
The Communities for Open Research Synthesis (COReS) project develops a framework to initiate systemic change in how preclinical research is translated into improved human health outcomes. Systematic review and meta-analysis are research synthesis tools that act as an evidence-based bridge to clarify existing knowledge, assess data reliability, and identify research gaps. We employ a three-pillar approach to integrate preclinical systematic reviews into the research pipeline.
Education: We enhance awareness and capacity through live workshops and a suite of freely available eLearning modules covering theall systematic review and meta-analysis steps. Our “train-the-trainer” programme scales this education by equipping trainers to teach this methodology at their institutions.
Infrastructure: To carry out systematic reviews, appropriate infrastructure and support is required. We build on existing software, the Systematic Review Facility (SyRF), improving user experience, documentation, and helpdesk services. New features are developed in collaboration with diverse user groups, and we integrate novel automation tools to reduce resource demands and streamline the systematic review process.
Community building: Forging communities to bridge the disconnect between primary research and evidence synthesis is instrumental in promoting an integrated research pipeline. Our digital hub brings together resources, tools, and support in one place. Our open online community forum fosters collaboration, standard sharing, and joint project development. Regular events spark new connections and dissemination of approaches.
Five German partner institutions are piloting this community blueprint to ensure adaptability across institutions and biomedical fields. By fostering interdisciplinary networks, COReS strengthens evidence-based decision-making and advances translational research.
Accepted Poster
Paper Short Abstract
Paper Abstract
The Communities for Open Research Synthesis (COReS) project develops a framework to initiate systemic change in how preclinical research is translated into improved human health outcomes. Systematic review and meta-analysis are research synthesis tools that act as an evidence-based bridge to clarify existing knowledge, assess data reliability, and identify research gaps. We employ a three-pillar approach to integrate preclinical systematic reviews into the research pipeline.
Education: We enhance awareness and capacity through live workshops and a suite of freely available eLearning modules covering theall systematic review and meta-analysis steps. Our “train-the-trainer” programme scales this education by equipping trainers to teach this methodology at their institutions.
Infrastructure: To carry out systematic reviews, appropriate infrastructure and support is required. We build on existing software, the Systematic Review Facility (SyRF), improving user experience, documentation, and helpdesk services. New features are developed in collaboration with diverse user groups, and we integrate novel automation tools to reduce resource demands and streamline the systematic review process.
Community building: Forging communities to bridge the disconnect between primary research and evidence synthesis is instrumental in promoting an integrated research pipeline. Our digital hub brings together resources, tools, and support in one place. Our open online community forum fosters collaboration, standard sharing, and joint project development. Regular events spark new connections and dissemination of approaches.
Five German partner institutions are piloting this community blueprint to ensure adaptability across institutions and biomedical fields. By fostering interdisciplinary networks, COReS strengthens evidence-based decision-making and advances translational research.
Poster session
Session 1 Tuesday 1 July, 2025, -