Short abstract:

To understand and anticipate gene drive innovation ecosystems, I examine how gene drives shape and are shaped by interwoven narratives of experience among diverse actors. I aim to centre experience in the innovation ecosystems concept via the disruptive potential of murine gene drives in Australia.

Long abstract:

Novel genetic biocontrol technologies, such as gene drives, are being developed for potential use in pest control, conservation, and public health. The ecosystems within which gene drives are developed and potentially deployed are therefore richly populated by individuals and groups whose relationships and practices are likely to be (re-)shaped by the technology. Responsible innovation requires that developers meld social and technical considerations in their designs to meet community expectations regarding both functionality and broader values. In other words, developers must consider what it will be like to live with gene drives, and how their design choices might support positive experiences.

In this paper I explore experience as a key feature of the innovation ecosystem concept, and as a basis for gene drive design. To do so, I draw on empirical research using variety of systems tools to qualitatively map the disruptive potential of a murine gene drive in South Australian pest management and conservation. By centering experience, I aim to expand and enrich the innovation ecosystem concept by highlighting subtle sources of resistance and support, which are rooted in people's day-to-day lives.

This research presents empirical findings that are relevant for the wider implementation of the innovation ecosystem concept. Furthermore, the research and its findings have implications for the field of responsible research and innovation, particularly regarding the application of experience-centred technology design.